TLDR - MARCoNS are bacteria that can live in the nasal passages and contribute to many of your CIRS symptoms. These bacteria can form biofilms that make them very difficult to eradicate.
Note that this should only be considered if you have been diagnosed with CIRS or have persistent sinus issues.
Symptoms
If you have CIRS, you will have many different symptoms. They all start to blend together and its hard to tell what is causing what. In reality, everything is a contributor. Below are a list of common MARCoNS symptoms though I would personally focus on the sinus issues when trying to diagnose.
Sinus Issues: Chronic sinusitis, nasal congestion, and facial pain.
Chronic Fatigue: Persistent exhaustion that does not improve with rest.
Brain Fog: Difficulty concentrating, memory issues, and general cognitive impairment.
Headaches: Frequent or severe headaches, including migraines.
Hormonal Imbalances: Symptoms can include mood swings, sleep disturbances, and irregularities in cortisol and MSH (Melanocyte Stimulating Hormone) levels.
Muscle and Joint Pain: Persistent pain and stiffness in muscles and joints.
Gastrointestinal Problems: Symptoms such as leaky gut, alternating constipation and diarrhea, and abdominal pain.
Increased Sensitivities: Heightened reactions to environmental toxins and things around you.
MARCoNS and CIRS:
MARCoNS are particularly problematic for CIRS patients because they contribute to chronic inflammation and immune dysregulation. They produce exotoxins that lower MSH levels, exacerbating symptoms and creating a cycle of chronic illness. The presence of MARCoNS can worsen other conditions associated with CIRS, making it crucial to diagnose and treat effectively.
Treatment
Eradicating MARCoNS can be very difficult. If you are not following the foundations then you will have an incredibly different time eliminating them and getting them to stay gone. Many people spend over a year trying to get rid of them and then they immediately come back if they are not taking maintenance sprays. Follow the foundations and you will support your body’s natural ways to fight off MARCoNS.
Nasal Sprays:
BEG Spray: Combines Bactroban (mupirocin), Gentamicin, and EDTA to break down biofilms and eliminate bacteria.
Colloidal Silver: Sometimes also used alone or in BEG sprays.
Environmental Control: Improve indoor air quality and reduce exposure to mold and toxins using air purifiers. When you remove external triggers, it gives your body a break and enhances its ability to fight off MARCoNS.
Binders: Activated charcoal, cholestyramine, and Welchol to bind and remove toxins.
Nasal Rinses: Some support the use saline solutions with additives like xylitol or hydrogen peroxide to clear infections and break down biofilms.
I personally used a BEG spray to get rid of MARCoNS. I started with a maintenance dose to keep it from coming back but then stopped after my foundations were solid. I would also highly recommend getting plenty of sun on your skin to increase MSH levels.